Autosomal dominant inheritance

Dominant inheritance. Photo: US National Library of Medicine

Although most genetic disorders involve inheriting a faulty gene from both parents, sometimes conditions are caused by inheriting a gene from just one parent.

In autosomal dominant inheritance you need only one copy of the faulty gene to be affected. This can come from either your mother or father.

Primary immunodeficiencies such as hyper IgE syndrome, known as Job’s syndrome, are inherited in an autosomal dominant pattern.